Take a Second
Partners in Health, which Joe Dressner has been repping all year, is a great charity and you should give them money:
International Volunteers in Urology is a charity I give to regularly. They are an organization of doctors and nurses who go around the world performing surgeries and most importantly, educating local doctors on surgical procedures. The doctors pay their own way, and take their own vacations to volunteer, but donations are needed for nurses and supplies:
Or choose any other charity you feel like.